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Usually there are a moderate angioedema, conjunctivitis, coughing, pruritus, rhinitis, rhinitis and urticaria. These reactions can occur irrespective of the dose, method of administration, and may be the first symptoms of a shock reaction. The introduction of contrast medium must be discontinued immediately and, if necessary, specific therapy initiated by venous access estrogen testosterone combination pillows.

Severe reactions requiring emergency treatment can be in the form dyscirculatory disorders accompanied by peripheral vasodilatation and subsequent hypotension, reflex tachycardia, respiratory disorder, agitation, impaired consciousness and cyanosis with a possible transition into unconsciousness.

Bronchospasm, laryngospasm or laryngeal edema and hypotension are rare reactions.

Rarely observed the delayed reaction to a contrast agent (see. “Special Instructions”).

  • Systemic reactions

Usually there are a burning sensation and headache. Malaise, chills or sweating and vasovagal reactions (syncope) are atypical.

In rare cases, a change in body temperature and swelling of salivary glands.

  • Respiratory system

Typical are transient changes in respiratory rate, shortness of breath, respiratory distress and cough. Respiratory arrest and pulmonary edema are rare reactions.

  • The cardiovascular system

Clinically significant transient changes in heart rate, blood pressure, arrhythmias or function and cardiac arrest are not typical.

Severe reactions requiring emergency treatment can be expressed in the form of peripheral vasodilatation and subsequent hypotension, reflex tachycardia, shortness of breath, excitement, disturbance of consciousness and cyanosis with a possible transition into unconsciousness.

On dangerous thromboembolic complications, leading to myocardial infarction, it has been reported rarely.


  • Digestive tract

Nausea and vomiting are typical reactions. Abdominal pain is not typical,

  • cerebral circulation

Cerebral angiography and other tests in which the contrast medium reaches the brain with arterial blood, may be accompanied by such neurological estrogen testosterone combination pillows complications related to atypical as dizziness, headache, agitation or disturbance of consciousness, amnesia, impaired speech, vision, hearing, convulsions, tremor, paresis / paralysis, photophobia, transient blindness, coma, drowsiness.

Severe thromboembolic complications, leading to a stroke, are a rare group.


  • kidneys

As described in rare cases renal dysfunction and renal failure

  • Leather

Typical reactions are: moderate angiogenic swelling, redness of the face with vasodilatation, rash, pruritus, erythema.

mucocutaneous syndrome may develop in rare cases (eg, Stevens-Johnson syndrome or Lyell’s syndrome).

  • Local irritation


Local pain observed mainly in peripheral angiography. Perivascular administration Urografin causes local pain, swelling, which usually disappear without the development of further complications. Inflammation and even tissue necrosis are described as extremely rare complications. Thrombophlebitis and venous thrombosis are not typical.

The introduction in the body cavity
after inserted into the body cavity side reactions are rare. Most of them occur within a few hours after administration because of the slow absorption from the area of administration and distribution in the body, the diffusion-controlled process.

During the ERCP is usually observed increase in amylase. Visualization of acini during ERCP is accompanied by an increased risk of subsequent pancreatitis. In rare cases described necrotic pancreatitis


  • Anaphylactoid reactions / hypersensitivity

System rare hypersensitivity reactions, and they are poorly expressed mainly manifested as skin reactions. However, the possibility of severe hypersensitivity reactions can not be excluded completely.

In case of accidental overdose or severely reduced renal function Urografin can be removed from the body by extracorporeal dialysis.

Interaction with other drugs
in patients receiving beta-blockers, hypersensitivity reactions are more pronounced.
The frequency of the delayed side effects (eg, fever, rash, flu-like symptoms, joint pain, itching) in the application of contrast media is higher in patients treated with interleukin.

Specific guidance
for all estrogen testosterone combination pillows indications
below mentioned precautions should be observed in all types of administration, but the risk of side effects above when administered intravenously.